New NBC sitcom set in Toledo

'A.P. Bio' to air next year

Glenn Howerton as Jack in ‘A.P. Bio.’

A.P. Bio is an upcoming classroom sitcom with a familiar setting: Toledo.

Just announced as a midseason replacement series for NBC next year, A.P. Bio is described as a single-camera comedy about an Ivy League philosophy scholar (Glenn Howerton from It’s Always Sunny in Philadelphia) who loses out on his dream job and goes to work as a high school Advanced Placement biology teacher in Toledo, where he makes it clear he will not be teaching any biology. Realizing he has a room full of honor roll students at his disposal, he opts to use the kids to his own benefit: revenge against those who wronged him.

The cast includes Patton Oswalt, Lyric Lewis, Mary Sohn, Aparna Brielle, Jacob McCarthy, Nick Peine, with Saturday Night Live’s Vanessa Bayer a guest star in the series pilot.

Former SNL writer Mike O’Brien will write and executive produce A.P. Bio, with Lorne Michaels, Seth Meyers, Andrew Singer, and Mike Shoemaker as executive producers.

The network recently ordered the pilot of A.P. Bio — its third pilot and first comedy of the season — to series.